Effexor xr - Effexor XR - Uses, Side Effects, and More Warnings: Antidepressant medications are used to treat a variety of conditions, including depression and other mental/ mood disorders. These medications...

 
Venlafaxine oral tablet is a prescription drug used to treat depression and social anxiety disorder (SAD). It comes in two forms: immediate-release (treats depression) and extended-release (treats .... Checkcoverage apple

The milder approach to mitigate long-term Effexor XR effects is the longer timeline. 7,20,21. Timing: If Effexor XR is usually taken in the morning, continue that schedule. Do not suddenly switch to taking it before bed or randomly during waking hours. Inpatient Care: Speak to your physician about inpatient care.Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ...May 7, 2021 · Pristiq and Effexor are two popular medications indicated for the treatment of depression, a common mental health condition. Effexor XR (extended-release) also treats generalized anxiety disorder, panic disorder, and social anxiety. Both drugs are approved by the United States Food and Drug Administration (FDA). Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ...After taking Effexor XR for some weeks or months, or even years, the body and CNS will have self-engineered various ways to adapt to the presence of the drug. 7 This process of the body’s “learned” adaptation is likely a key part of how Effexor addiction or dependence gets laid in. The body begins to change how these neurochemicals are ...EA. Earth2missy 31 Jan 2022. I have been taking Effexor XR for over 15 years and definitely have terrible side effects if I miss one dose at night. I take them at bedtime because they make me sick. If I miss it at nite by mid morning I am feeling extremely sad, teary, make bad decisions, and emotional, nauseous.Worked well for depression but caused me to gain lots of weight. Eventually stopped working. Takes forever to gets off. Even while weaning down by 1/4 every 2 weeks, lots of nausea, diarrhea, brain zaps, tears, headaches, sleep disturbances, and general major physical discomfort. Am on 37.5 now (last taper) and honestly just hate it so much, my ...Effexor XR can cause side effects that range from mild to serious. Examples include weight changes, sweating, and high blood pressure. Effexor XR is used in adults to treat: major depressive ...Effexor XR (venlafaxine) is used to treat major depressive disorder, anxiety, and panic disorder. Includes Effexor XR side effects, interactions and indications.In one longer-term study, adult outpatients meeting DSM-IV criteria for major depressive disorder who had responded during an 8-week open trial on Effexor XR (75, 150, or 225 mg, qAM) were randomized to continuation of their same Effexor XR dose or to placebo, for up to 26 weeks of observation for relapse.My neurologist and psychiatrist both suggested Effexor since it can help with migraines and chronic pain. I was scared of the withdrawal and possible side effects and all these reviews but the headaches were so frequent I needed to do som. 1. Report this post. Viatris reserves the right to rescind, revoke, or amend the program without notice. No membership fees. This Savings Offer and Program expire on 12/31/2023. For help with the EFFEXOR XR Savings Offer, call 1-855-488-0750, visit EFFEXORXR.com, or write: Viatris, P.O. Box 2941, Mission, KS 66201. Jul 11, 2023 · Effexor XR may cause serious side effects. Call your doctor at once if you have: blurred vision, eye pain or redness, seeing halos around lights; What Is Venlafaxine (Effexor, Effexor XR) and How Does It Work? Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder ( social phobia ). It may improve your mood and energy level and may help restore your interest in daily living.Effexor XR is indicated for the treatment of Social Anxiety Disorder (SAD), also known as social phobia. Efficacy was established in four 12-week and one 26-week, placebo-controlled trials. 1.4 Panic Disorder Effexor XR is indicated for the treatment of Panic Disorder (PD), with or without agoraphobia. Efficacy 1-3 days after the last dose. During the first few days of Effexor detox, mild withdrawal symptoms may start to appear. 4-5 days after the last dose. Withdrawal symptoms often become more intense several days into Effexor detox and they may include nausea, shakiness, dizziness, and insomnia, among others. 1-3 weeks after the last dose.Aug 1, 2023 · Effexor; Effexor-XR; Descriptions. Venlafaxine is used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine belongs to a group of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRI). You may have an increased risk of side effects (eg, mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, increased sweating, diarrhea, nausea, vomiting, trouble sleeping, or unusual tiredness. If you need to stop Effexor, your doctor may need to gradually lower your dose.Jan 16, 2023 · Effexor XR (venlafaxine) is a prescription capsule that’s used to treat depression, anxiety, and panic disorder. Learn about side effects, dosage, and more. Effexor XR has an average rating of 6.8 out of 10 from a total of 110 reviews for the treatment of Generalized Anxiety Disorder. 57% of reviewers reported a positive experience, while 24% reported a negative experience. Filter by condition.Jul 11, 2023 · Venlafaxine is also known as: Effexor, Effexor XR. Pregnancy Warnings; Breastfeeding Warnings; Venlafaxine Pregnancy Warnings. Animal studies have revealed increased perinatal toxicity and fetotoxicity at doses potentially correlated with maternal toxicity. There are no controlled data in human pregnancy. Effexor XR is indicated for the treatment of Social Anxiety Disorder (SAD), also known as social phobia. Efficacy was established in four 12-week and one 26-week, placebo-controlled trials. 1.4 Panic Disorder . Effexor XR is indicated for the treatment of Panic Disorder (PD), with or without agoraphobia. EfficacyMay 7, 2021 · Pristiq and Effexor are two popular medications indicated for the treatment of depression, a common mental health condition. Effexor XR (extended-release) also treats generalized anxiety disorder, panic disorder, and social anxiety. Both drugs are approved by the United States Food and Drug Administration (FDA). Mechanism of Action. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine reuptake. Venlafaxine and ODV have no significant activity for muscarinic cholinergic, H 1 -histaminergic, or alpha 2 -adrenergic receptors.My neurologist and psychiatrist both suggested Effexor since it can help with migraines and chronic pain. I was scared of the withdrawal and possible side effects and all these reviews but the headaches were so frequent I needed to do som. 1. Report this post.Antidepressants may increase risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (18–24 years of age) with major depressive disorder and other psychiatric disorders; balance this risk with clinical need. Venlafaxine is not approved for use in pediatric patients. (See Pediatric Use under Cautions.)Here are the things that helped me with the physical withdrawal symptoms: 1. Get plenty of sleep/rest. 2. Eat a very well-balanced diet (this is not the time to worry about your weight.) Lots of soup & easy to digest foods the 1st few days. 3. Drink plenty of water, including coconut water. 4.Jan 18, 2010 · EA. Earth2missy 31 Jan 2022. I have been taking Effexor XR for over 15 years and definitely have terrible side effects if I miss one dose at night. I take them at bedtime because they make me sick. If I miss it at nite by mid morning I am feeling extremely sad, teary, make bad decisions, and emotional, nauseous. Find patient medical information for Effexor oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Sep 23, 2022 · Some dosage forms listed on this page may not apply to the brand name Effexor XR. Summary Common side effects of Effexor XR include: anorgasmia, asthenia, constipation, dizziness, drowsiness, headache, insomnia, nausea, nervousness, anorexia, decreased appetite, delayed ejaculation, diaphoresis, and xerostomia. كبسولات ايفيكسور اكس ار ( EFEXOR XR ) , امراض نفسية ينتمي العلاج إلى عائلة مثبطات استرداد السيريتونين و النورأدرنالين الانتقائية، والتي تعمل على زيادة نسبة النواقل العصبي...Nov 4, 2022 · Sertraline (Zoloft), paroxetine (Paxil), and venlafaxine ER (Effexor XR) are FDA-approved medications for social anxiety disorder. Non-medication treatments, such as cognitive behavioral therapy (CBT) and support groups, may be helpful in relieving anxiety symptoms. Ivan Pantic/E+ via Getty Images. Both Pristiq and Effexor have a similar number of common side effects. For both, most of the common side effects typically go away within 1 to 2 weeks of starting the medication.. They both can ...Jan 16, 2023 · Effexor XR (venlafaxine) is a prescription capsule that’s used to treat depression, anxiety, and panic disorder. Learn about side effects, dosage, and more. Effexor XR - Uses, Side Effects, and More Warnings: Antidepressant medications are used to treat a variety of conditions, including depression and other mental/ mood disorders. These medications...Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ...Effexor (venlafaxine) is considered "weight neutral" because weight changes, if there are any at all, can go either way: "Very common (10% or more of users): Anorexia (up to 20%) Common (1% to 10% of users): Decreased appetite, increased appetite, weight gain, weight loss". Note that most people do not experience any weight change.Effexor is an antidepressant used to treat the symptoms of major depressive disorder. The interaction between this and alcohol can be dangerous to one’s health, possibly resulting in far-reaching health implications, addictive effects, and sudden death. Therefore, it is highly advised against mixing these two substances. Always consult your doctor toPristiq and Effexor are two popular medications indicated for the treatment of depression, a common mental health condition. Effexor XR (extended-release) also treats generalized anxiety disorder, panic disorder, and social anxiety. Both drugs are approved by the United States Food and Drug Administration (FDA).After taking Effexor XR for some weeks or months, or even years, the body and CNS will have self-engineered various ways to adapt to the presence of the drug. 7 This process of the body’s “learned” adaptation is likely a key part of how Effexor addiction or dependence gets laid in. The body begins to change how these neurochemicals are ...Both Pristiq and Effexor have a similar number of common side effects. For both, most of the common side effects typically go away within 1 to 2 weeks of starting the medication.. They both can ...Effexor (venlafaxine) is considered "weight neutral" because weight changes, if there are any at all, can go either way: "Very common (10% or more of users): Anorexia (up to 20%) Common (1% to 10% of users): Decreased appetite, increased appetite, weight gain, weight loss". Note that most people do not experience any weight change.Some dosage forms listed on this page may not apply to the brand name Effexor XR. Summary Common side effects of Effexor XR include: anorgasmia, asthenia, constipation, dizziness, drowsiness, headache, insomnia, nausea, nervousness, anorexia, decreased appetite, delayed ejaculation, diaphoresis, and xerostomia.Venlafaxine is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD; excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear ... Viatris reserves the right to rescind, revoke, or amend the program without notice. No membership fees. This Savings Offer and Program expire on 12/31/2023. For help with the EFFEXOR XR Savings Offer, call 1-855-488-0750, visit EFFEXORXR.com, or write: Viatris, P.O. Box 2941, Mission, KS 66201.Apr 17, 2016 · Effexor is a tricky one but at least your switching to another SNRI. If your Dr will Rx you the instant release they make 100, 75, 50, 37.5, and 25mg tabs that can be split safely and ideally I would go 250x5, 200x5, 150x5, then 75x5 but add the 30 of Cymbalta then after 5 days I would go to the 60mg dose. Both of the others that answered are ... venlafaxine (Effexor) 300. 225. 150. 75. 37.5. duloxetine* (Cymbalta) 90. 60. 30. 20 : bupropion* (Wellbutrin) 300. 200. 150. 100 +Alternate 40 mg one day and 20 the next to get the equivalent of 30 mg per day. ++Take 20 mg every other day to get the equivalent of 10 mg per day. *Pill should not be cut.Jan 16, 2023 · Effexor XR (venlafaxine) is a prescription capsule that’s used to treat depression, anxiety, and panic disorder. Learn about side effects, dosage, and more. I started on Effexor xr 37.5mg for depression about a month ago and noticed a slight decrease in sex drive and it was extremely hard to orgasm. In two more weeks the Doc upped my dose to 75mg and gradually over the next few days my sex drive increased. Now after 3 weeks on the 75mg my sex drive has surpassed my normal non-drugged sex drive.كبسولات ايفيكسور اكس ار ( EFEXOR XR ) , امراض نفسية ينتمي العلاج إلى عائلة مثبطات استرداد السيريتونين و النورأدرنالين الانتقائية، والتي تعمل على زيادة نسبة النواقل العصبي...Mar 14, 2023 · Effexor XR can cause side effects that range from mild to serious. Examples include weight changes, sweating, and high blood pressure. Effexor XR is used in adults to treat: major depressive ... Effexor XR (venlafaxine hydrochloride) extended-release capsules are indicated for the treatment of major depressive disorder (MDD). Efficacy was established in three short-term (4, 8, and 12 weeks) and two long-term, maintenance trials. Generalized Anxiety Disorder. Effexor XR is indicated for the treatment of Generalized Anxiety Disorder ...Effexor XR, the more popularly prescribed type of Effexor, is covered by most insurance and Medicare prescription plans. The generic version will have a lower copay, and the brand name may have a higher copay or may not be covered.Effexor XR can cause side effects that range from mild to serious. Examples include weight changes, sweating, and high blood pressure. Effexor XR is used in adults to treat: major depressive ...May 4, 2022 · Effexor XR (Venlafaxine HCl): Uses, Dosage, Side Effects, and More Effexor XR (venlafaxine HCl) is a medication used to treat a variety of anxiety disorders like generalized anxiety disorder, panic disorder, and social phobia, as well as clinical depression (also referred to as major depressive disorder or MDD). Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood, anxiety, and lack of interest in activities may need up to 6-8 weeks to fully improve." Venlafaxine (Effexor) | NAMI: National Alliance on Mental Illness. +0.Effexor, also known as venlafaxine, is an antidepressant medication. ... Under the name Effexor, it is only available as the XR version. Generic versions are available in both immediate release ...Brand names for venlafaxine include Effexor XR. The cost for venlafaxine oral capsule, extended release 75 mg is around $22 for a supply of 30 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans.Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ...Both Pristiq and Effexor have a similar number of common side effects. For both, most of the common side effects typically go away within 1 to 2 weeks of starting the medication.. They both can ...Brand names: Effexor XR, Effexor Dosage forms: oral capsule, extended release (150 mg; 37.5 mg; 75 mg), oral tablet (100 mg; 25 mg; 37.5 mg; 50 mg; 75 mg), ... show all 3 dosage forms Drug class: Serotonin-norepinephrine reuptake inhibitorsINDICATIONS. EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).The tramadol affects the mu opoid receptors in the brain while the Effexor does not. While the tramadol does have antidepressant properties by affecting the two neurotransmitters mentioned, it is not meant to treat depression like the Effexor is. If the goal is pain control, the tramadol is recommended while if the goal is depression control ...I never had anxiety, insomnia, akathisia, irritability and rage UNTIL I tapered off (last dose was 4/14/18). Effexor increases/regulates the levels of two brain neurotransmitters–norepinephrine (noradrenaline) and serotonin. At low doses, it prevents serotonin reuptake (leaves more serotonin in the system).I too began having seizures after being prescribed Effexor XR, along with other medications. The psychiatrist attributed my seizures to anything but the prescribed drugs. I was misdiagnosed as having epilepsy by a neurologist who claimed to not know the specific causation of my seizures. Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ...Effexor is an antidepressant that may cause a discontinuation syndrome if abruptly stopped after long-term administration. 5. Tips. Take Effexor with food. Swallow Effexor XR capsules whole; do not break, crush, chew or attempt to dissolve in water.Nov 16, 2022 · Yes, there is a recommended dosage range. The lowest dose and highest dose per day depend on the condition you are taking Effexor XR to treat. For most indications, the lowest dosage is 37.5 milligrams (mg) per day and the highest dosage is 225 mg per day. For social anxiety disorder, the typical dosage is 75 mg per day. Apr 26, 2023 · How to Take Effexor . Effexor XR is taken once each day. Typical doses range from 37.5 mg to 225 mg, with a typical target dose of 75 mg per day. Your healthcare provider will typically start at a lower amount and gradually increase the dose until they determine the right dose for you. Effexor XR - Uses, Side Effects, and More Warnings: Antidepressant medications are used to treat a variety of conditions, including depression and other mental/ mood disorders. These medications...Nov 16, 2022 · Yes, there is a recommended dosage range. The lowest dose and highest dose per day depend on the condition you are taking Effexor XR to treat. For most indications, the lowest dosage is 37.5 milligrams (mg) per day and the highest dosage is 225 mg per day. For social anxiety disorder, the typical dosage is 75 mg per day. Effexor XR is indicated for the treatment of Social Anxiety Disorder (SAD), also known as social phobia. Efficacy was established in four 12-week and one 26-week, placebo-controlled trials. 1.4 Panic Disorder Effexor XR is indicated for the treatment of Panic Disorder (PD), with or without agoraphobia. EfficacySep 19, 2022 · Two 6-month studies, one evaluating Effexor XR doses of 37.5, 75, and 150 mg per day (study 3) and the other evaluating Effexor XR doses of 75 to 225 mg per day (study 4), showed that daily doses of 75 mg or higher were more effective than placebo on the HAM-A total, both the HAM-A anxiety and tension items, and the CGI scale during 6 months of ... EA. Earth2missy 31 Jan 2022. I have been taking Effexor XR for over 15 years and definitely have terrible side effects if I miss one dose at night. I take them at bedtime because they make me sick. If I miss it at nite by mid morning I am feeling extremely sad, teary, make bad decisions, and emotional, nauseous.EFFEXOR XR may cause serious side effects, including: Increased risk of suicidal thoughts and actions. EFFEXOR XR and other antidepressant medicines may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for ... Aug 1, 2023 · Effexor; Effexor-XR; Descriptions. Venlafaxine is used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine belongs to a group of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRI). Venlafaxine oral tablet is a prescription drug used to treat depression and social anxiety disorder (SAD). It comes in two forms: immediate-release (treats depression) and extended-release (treats ...Mechanism of Action. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine reuptake. Venlafaxine and ODV have no significant activity for muscarinic cholinergic, H 1 -histaminergic, or alpha 2 -adrenergic receptors.

Apr 17, 2016 · Effexor is a tricky one but at least your switching to another SNRI. If your Dr will Rx you the instant release they make 100, 75, 50, 37.5, and 25mg tabs that can be split safely and ideally I would go 250x5, 200x5, 150x5, then 75x5 but add the 30 of Cymbalta then after 5 days I would go to the 60mg dose. Both of the others that answered are ... . Mantis x rule34

effexor xr

Nov 4, 2022 · Sertraline (Zoloft), paroxetine (Paxil), and venlafaxine ER (Effexor XR) are FDA-approved medications for social anxiety disorder. Non-medication treatments, such as cognitive behavioral therapy (CBT) and support groups, may be helpful in relieving anxiety symptoms. Ivan Pantic/E+ via Getty Images. Satisfaction. This medication is EXTREMELY addictive. It will cause horrible side effects. Dizziness, brain zaps, severe mood swings, nausea And just overall feeling unlike anything you have ever experienced trying to get off this medicine. They say opiods are addictive. If they're more addictive than effexor.Jul 11, 2023 · Effexor XR may cause serious side effects. Call your doctor at once if you have: blurred vision, eye pain or redness, seeing halos around lights; Nov 18, 2021 · Effexor XR (venlafaxine hydrochloride) extended-release capsules are indicated for the treatment of major depressive disorder (MDD). Efficacy was established in three short-term (4, 8, and 12 weeks) and two long-term, maintenance trials. Generalized Anxiety Disorder. Effexor XR is indicated for the treatment of Generalized Anxiety Disorder ... Venlafaxine. Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. [5] [8] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [8] Studies have shown that Venlafaxine ...Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood, anxiety, and lack of interest in activities may need up to 6-8 weeks to fully improve." Venlafaxine (Effexor) | NAMI: National Alliance on Mental Illness. +0.Loss of libido (sex drive) was a common side effect in males* and females* taking Effexor XR. Other sexual side effects in males may include: abnormal ejaculation. erectile dysfunction (inability ...After taking Effexor XR for some weeks or months, or even years, the body and CNS will have self-engineered various ways to adapt to the presence of the drug. 7 This process of the body’s “learned” adaptation is likely a key part of how Effexor addiction or dependence gets laid in. The body begins to change how these neurochemicals are ...كبسولات ايفيكسور اكس ار ( EFEXOR XR ) , امراض نفسية ينتمي العلاج إلى عائلة مثبطات استرداد السيريتونين و النورأدرنالين الانتقائية، والتي تعمل على زيادة نسبة النواقل العصبي...What is the most important information I should know about EFFEXOR XR? EFFEXOR XR may cause serious side effects, including:. Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed.Some dosage forms listed on this page may not apply to the brand name Effexor XR. Summary Common side effects of Effexor XR include: anorgasmia, asthenia, constipation, dizziness, drowsiness, headache, insomnia, nausea, nervousness, anorexia, decreased appetite, delayed ejaculation, diaphoresis, and xerostomia.What Is Venlafaxine (Effexor, Effexor XR) and How Does It Work? Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder ( social phobia ). It may improve your mood and energy level and may help restore your interest in daily living. Effexor XR can cause side effects that range from mild to serious. Examples include weight changes, sweating, and high blood pressure. Effexor XR is used in adults to treat: major depressive ...Viatris reserves the right to rescind, revoke, or amend the program without notice. No membership fees. This Savings Offer and Program expire on 12/31/2023. For help with the EFFEXOR XR Savings Offer, call 1-855-488-0750, visit EFFEXORXR.com, or write: Viatris, P.O. Box 2941, Mission, KS 66201. Feb 17, 2020 · Mechanism of Action. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak inhibitors of dopamine reuptake. Venlafaxine and ODV have no significant activity for muscarinic cholinergic, H 1 -histaminergic, or alpha 2 -adrenergic receptors. .

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